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Pneumocystis jirovecii pneumonie (PCP/PJP)

Advices

≥ 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

cotrimoxazol (trimethoprim +sulfamethoxazol) iv 1920mg 3dd

Remarks:

kan ook per os

Priority:
2nd choice
Medication:

clindamycine iv 600mg 4dd

+

primaquine po 30mg 1dd

Remarks:

bij overgevoeligheid sulfamethoxazol

cave G6PD-deficiëntie

≥ 18 years

Indications: bij niet-ernstige infectie

Priority Medication Remarks
Priority:
2nd choice alternative
Medication:

trimethoprim po 300mg 3dd

+

dapsone po 100mg 1dd

Remarks:

bij overgevoeligheid sulfamethoxazol

cave G6PD-deficiëntie

Priority:
3rd choice
Medication:

atovaquon po 750mg 2dd

Remarks:

suspensie, innemen met voedsel

≥ 18 years

Indications: Bij ernstige infectie

Priority Medication Remarks
Priority:
2nd choice alternative
Medication:

pentamidine iv 4mg/kg 1dd

General comments

Bij pO2 < 70 mm Hg of 8-9 kPa toevoegen prednison:

dag 1-5 2 dd 40 mg;
dag 6-10 2 dd 20 mg;
dag 11-14 1 dd 20 mg

Totale behandelduur 14-21 dagen

Na behandeling zo nodig secundaire profylaxe starten

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-436055.3
Updated: 02/22/2021 - 10:12
Status: Published