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mediastinitis

Advices

≥ 18 years
Priority Medication Remarks
Medication:

amoxicilline + clavulaanzuur iv 1000/200mg 6dd

Remarks:

Na perforatie tr. digestivus: community-accquired

Medication:

amoxicilline + clavulaanzuur iv 1000/200mg 6dd

+

gentamicine iv 7mg/kg one-off

Remarks:

Na perforatie tr. digestivus: na manipulatie of ingreep

Medication:

flucloxacilline iv 1000mg 6dd

+

gentamicine iv 7mg/kg one-off

Remarks:

Postoperatief na sternotomie

General comments

Op geleide van kweek wordt de therapie aangepast.

De behandelduur is 2-6 weken.

Bij penicilline / betalactam allergie, zie https://zhz.adult.swabid.nl/node/424023

Sources

  1. Pubmed.gov publication # 31306791

    Pastene B, et al. Mediastinitis in the intensive care unit patient: a narrative review. Clin Microbiol Infect. 2020 Jan;26(1):26-34.

TDM Alert
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-500079.2
Updated: 12/23/2021 - 16:49
Status: Published